TRACKERLESS NAVIGATION PLATFORM

Powering AI-Assisted Surgery across orthopaedics and spine

  • We develop an AI-based, trackerless navigation approach that derives spatial intelligence from standard X-ray imaging without external optical tracking systems or reference frames, operating with unmodified surgical instruments and existing imaging equipment.

    This architecture enables seamless integration with semi-automated and next-generation robotic systems while simplifying workflow and reducing operating room complexity.

    The platform is adaptable to AI-Assisted Surgery workflows across orthopaedics, including spine, trauma, and joint reconstruction.
  • Regulatory Notice:
    metamorphosis GmbH is the legal manufacturer and FDA 510(k) holder of VELYS™ Trauma, an image-processing software indicated to assist with intraoperative positioning of femur fracture implant components in adult patients. VELYS is a registered trademark of DePuy Synthes, Inc., a Johnson & Johnson company.
    Certain additional technologies and prototype concepts described on this website are under development and are not cleared or approved by the U.S. FDA or CE marked.

Impossible?

Challenging perceived wisdoms in computer-assisted and robotic surgery

  • For decades, surgical navigation has relied on optical trackers, reference arrays, and hardware add-ons.

    We question whether this complexity is inherent. We believe navigation can be redefined through imaging-native intelligence. Our work explores a trackerless paradigm designed to simplify workflow without compromising spatial accuracy.

    Witness the metamorphosis.



    Certain technologies described here are under development and are not cleared for clinical use.
30+ granted patents
100+ pending patents
40+ team members
ISO 13485 certified quality management system

LEADERSHIP TEAM

  • Prof. Peter Schreier, Ph.D. Co-Founder & Chief Executive Officer
    Peter holds a Ph.D. in electrical engineering from the University of Colorado at Boulder, USA. His background spans more than 20 years across academia and industry on four continents, with a focus on signal processing, data science, and complex technical systems. He has led large research and engineering teams and served as Professor and Dean at Paderborn University, Germany.
  • Dipl.-Ing. Arno Blau Co-Founder & Chief Technology Officer
    Arno is a graduate in electrical engineering from Technical University of Munich, Germany. He has more than 20 years of R&D and management experience developing Computer-Assisted-Surgery systems, including at industry leaders Brainlab and Stryker. Arno is an inventor of more than 150 pending patent applications and granted patents in the field of surgical navigation.

MEDICAL ADVISORY BOARD

  • Peter Derman, M.D. Texas Back Institute, Plano, TX, USA
    Dr. Derman is a minimally invasive and endoscopic spine surgeon. In addition to his clinical responsibilities, he is active in teaching, research, and product development. He has served in leadership roles in multiple national and international spine societies and was a founding member of both the Endoscopic Spine Research Group and the International Spinal Endoscopy Research Foundation.
  • Prof. Michael Gardner, M.D. Professor & Chief of the Orthopaedic Trauma Service and Vice Chair of Clinical Operations, Stanford University Hospital, USA
    Dr. Gardner specializes in orthopaedic trauma surgery, and treating all aspects of fractures of the upper extremity (except the hand), lower extremity, and pelvis, as well as nonunions and malunions. He has published over 180 scientific articles and 38 book chapters, and edited 5 textbooks on mastering advanced surgical techniques in fracture surgery.
  • Dr. med. Lutz Mahlke Chief of Orthopaedics, Trauma, and Sport Traumatology at St. Vincenz Hospital, Paderborn, Germany
    Dr. Mahlke specializes in pelvis and hip surgery, with many years of experience in navigation, 3D imaging, and hybrid surgery. He has been Chief of Orthopaedics, Trauma, and Sport Traumatology at St. Vincenz Hospital, Paderborn, since 2009. Since 2018 he has served on the Advisory Board of AO Trauma Germany.
  • Prof. Cyril Mauffrey, M.D. Chief, Dept. of Orthopedics, Rehabilitation and Physical Therapy at Denver Health Medical Center and Professor of Orthopedics at the Colorado University School of Medicine
    Dr. Mauffrey is Editor-in-Chief for the European Journal of Orthopedics and serves on several other editorial boards. He travels nationally and internationally to give talks on orthopaedic trauma, particularly on pelvic and acetabular fractures. With over 200 peer-reviewed publications, book chapters, and textbooks on orthopaedic trauma, his research focuses on the treatment and outcomes following complex pelvic and acetabular fractures.
  • Prof. Sean E. Nork, M.D. Professor & Trauma Section Chief, Orthopedic Trauma Surgery Clinic at Harborview Medical Center, University of Washington, USA
    Dr. Nork's clinical interests include orthopaedic traumatology, non-union fractures, periarticular fractures and pilon fractures. He is the Chief of Orthopaedic Trauma at Harborview Medical Center and the University of Washington where he has worked for over 20 years. Dr. Nork has published more than 80 peer-reviewed scientific articles and presented at numerous medical meetings.
  • PROF. TIMOTHY WITHAM, M.D. Professor of Neurosurgery and Orthopaedic Surgery & Director, The Johns Hopkins Neurosurgery Spinal Fusion laboratory, The Johns Hopkins University, USA
    Dr. Witham specializes in spinal deformity and degenerative diseases of the spine. He has been a leader in the field of Augmented Reality guided spinal surgery. He has published over 250 peer reviewed scientific manuscripts, has lectured nationally and internationally, has authored multiple book chapters and sits on the editorial review boards for several journals.

Join our team

Help build the next generation of surgical navigation

  • We are building imaging-native navigation technology for orthopaedic surgery and are looking for exceptional engineers and scientists.

    Our work sits at the intersection of AI, medical imaging, computer vision, robotics, and surgical workflow. You will tackle complex geometric and algorithmic challenges, contribute to real-world systems used in demanding clinical environments, and help shape a new generation of navigation technology.
  • Explore open roles at career.metamorphosis.ai

CONTACT US

VISIT OR WRITE TO US

metamorphosis GmbH
Technologiepark 9
33100 Paderborn, Germany

E-MAIL US

info@metamorphosis.ai

CALL US

+49 5251 2971680