AI-Assisted Surgery

At metamorphosis, we push the boundaries of what’s technically possible in surgical navigation and robotics. We research how artificial intelligence can reshape the future of orthopaedic and spinal procedures — aimed at making guidance smarter, faster, and more reliable.

  • We are developing technologies for 3D navigation that do not rely on external trackers and reference bodies. Based on numerous granted patents for generating 3D navigation information from a single 2D X-ray image in near real time, this vision has been demonstrated in wet-lab prototypes. By analyzing intra-operative imaging rather than external markers, our goal is to enhance the reliability and robustness of future navigation systems.
  • Prototype concepts under development. Not cleared or approved by the U.S. FDA or CE marked. Not for clinical use or sale in any jurisdiction.

Impossible?

Challenging perceived wisdoms in computer-assisted and robotic surgery

  • For decades, computer-assisted and robotic systems have required complex apparatuses and additional procedural steps. In spinal surgery, automation remains a controversial frontier.

    At metamorphosis, we explore how advances in artificial intelligence, imaging, and augmented reality can redefine surgical navigation. Together with leading clinicians and research partners, we are investigating technologies that have the potential to simplify workflows and expand surgical possibilities.

    Witness the metamorphosis.



    Prototype concepts under development. Not cleared or approved by the U.S. FDA or CE marked. Not for clinical use or sale in any jurisdiction.
25 granted patents
80+ pending patents
40+ team members
ISO 13485 certified quality management system

LEADERSHIP TEAM

  • Prof. Peter Schreier, Ph.D. Chief Executive Officer
    Peter holds a Ph.D. in electrical engineering from the University of Colorado at Boulder, USA. He has more than 20 years of research and leadership experience in various roles in academia and industry on four continents. Peter has a concurrent appointment as Professor of Electrical Engineering and IT at Paderborn University.
  • Dipl.-Ing. Arno Blau Chief Technology Officer
    Arno is a graduate in electrical engineering from Technical University of Munich, Germany. He has more than 20 years of R&D and management experience developing Computer-Assisted-Surgery systems, including at industry leaders Brainlab and Stryker. Arno is an inventor of more than 100 pending patent applications and granted patents.
  • Dr. med. Jürgen Schmidt Chief Medical Officer
    Jürgen completed his medical education at Ludwig-Maximilians-University in Munich, Germany. He has extensive experience as a senior trauma surgeon, emergency physician, and team leader at Augsburg University Hospital, one of the largest Level I trauma centers in Germany. Jürgen has always had a passion for innovation in the OR.

MEDICAL ADVISORY BOARD

  • Peter Derman, M.D. Texas Back Institute, Plano, TX, USA
    Dr. Derman is a minimally invasive and endoscopic spine surgeon. In addition to his clinical responsibilities, he is active in teaching, research, and product development. He has served in leadership roles in multiple national and international spine societies and was a founding member of both the Endoscopic Spine Research Group and the International Spinal Endoscopy Research Foundation.
  • Prof. Michael Gardner, M.D. Professor & Chief of the Orthopaedic Trauma Service and Vice Chair of Clinical Operations, Stanford University Hospital, USA
    Dr. Gardner specializes in orthopaedic trauma surgery, and treating all aspects of fractures of the upper extremity (except the hand), lower extremity, and pelvis, as well as nonunions and malunions. He has published over 180 scientific articles and 38 book chapters, and edited 5 textbooks on mastering advanced surgical techniques in fracture surgery.
  • Dr. med. Lutz Mahlke Chief of Orthopaedics, Trauma, and Sport Traumatology at St. Vincenz Hospital, Paderborn, Germany
    Dr. Mahlke specializes in pelvis and hip surgery, with many years of experience in navigation, 3D imaging, and hybrid surgery. He has been Chief of Orthopaedics, Trauma, and Sport Traumatology at St. Vincenz Hospital, Paderborn, since 2009. Since 2018 he has served on the Advisory Board of AO Trauma Germany.
  • Prof. Cyril Mauffrey, M.D. Chief, Dept. of Orthopedics, Rehabilitation and Physical Therapy at Denver Health Medical Center and Professor of Orthopedics at the Colorado University School of Medicine
    Dr. Mauffrey is Editor-in-Chief for the European Journal of Orthopedics and serves on several other editorial boards. He travels nationally and internationally to give talks on orthopaedic trauma, particularly on pelvic and acetabular fractures. With over 200 peer-reviewed publications, book chapters, and textbooks on orthopaedic trauma, his research focuses on the treatment and outcomes following complex pelvic and acetabular fractures.
  • Prof. Sean E. Nork, M.D. Professor & Trauma Section Chief, Orthopedic Trauma Surgery Clinic at Harborview Medical Center, University of Washington, USA
    Dr. Nork's clinical interests include orthopaedic traumatology, non-union fractures, periarticular fractures and pilon fractures. He is the Chief of Orthopaedic Trauma at Harborview Medical Center and the University of Washington where he has worked for over 20 years. Dr. Nork has published more than 80 peer-reviewed scientific articles and presented at numerous medical meetings.
  • PROF. TIMOTHY WITHAM, M.D. Professor of Neurosurgery and Orthopaedic Surgery & Director, The Johns Hopkins Neurosurgery Spinal Fusion laboratory, The Johns Hopkins University, USA
    Dr. Witham specializes in spinal deformity and degenerative diseases of the spine. He has been a leader in the field of Augmented Reality guided spinal surgery. He has published over 250 peer reviewed scientific manuscripts, has lectured nationally and internationally, has authored multiple book chapters and sits on the editorial review boards for several journals.

Join our team

Revolutionize orthopaedic surgery together with us!

  • Are you looking for an exciting challenge in an environment that values creativity, curiosity, and critical thinking? Do you want to be at the forefront of artificial intelligence and computer-assisted surgery? Do you want a truly meaningful job and not just programming the latest app?

    Then metamorphosis is the right place for you!

    We offer careers tackling exciting challenges in surgical navigation and robotics for minimally invasive orthopaedic and spinal procedures. Your work will contribute to innovations that have the potential to improve the lives of millions of people.
  • Click here to go to our careers website: career.metamorphosis.ai

CONTACT US

VISIT OR WRITE TO US

metamorphosis GmbH
Technologiepark 9
33100 Paderborn, Germany

E-MAIL US

info@metamorphosis.ai

CALL US

+49 5251 2971680